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Alnylam Pharmaceuticals (ALNY, Biotech) Stock Valuation & Fair Value

Mixed on our tests

Alnylam Pharmaceuticals (ALNY, Biotech) trades at a current P/E of 9.0, a multiple its historical normal P/E is too distorted to compare with, with a forward growth estimate of -20.2%. Analysts' one-year estimates have been hit 27% of the time.

How to read these numbers: the PEG ratio and current P/E versus normal P/E.

The historical normal P/E published for Alnylam Pharmaceuticals is 170.7, more than six times its current multiple. A gap that wide comes from the company's earnings history rather than from its price, so this page quotes no premium or discount against it.

Current P/E
9.0
Normal P/E
not meaningful
PEG
—
Fwd growth
-20.2%
Div yield
0.0%
RSI (14)
21.9
Oversold
Technical context
  • Price $155.94 at the Nov 6 close, 23.9% below the 20-day average ($204.95) and 31.8% below the 50-day ($228.57).
  • RSI (14) at 21.9.
  • 52-week range $155.94 to $473.29: the price is 67.1% below the high and at the low.

The Street vs SeerForecast

Wall Street's mean price target for ALNY is $310.89 across 27 analysts, 99.4% above the current price. The average analyst rating is Buy. Our SeerForecast read of the same stock, formed without analyst targets: mixed on our tests. When the two disagree, start your digging there.

Valuation flags

Verdict history

tickerseer's rating moved from favorable on our tests (2026-07-25) to mixed on our tests (2026-11-02). New rating rules took effect in the week of 2026-09-28, and this rating moved across that change, so part of the move may come from the new rules rather than the company.

Current P/E and rating by weekCurrent P/E moved from 54.6 to 9.7 between 2026-07-24 and 2026-10-30, with 1 rating change over 15 recorded weeks.2026-07-24: P/E 54.6, Favorable on our tests, recalculated for the week of 2026-07-252026-07-27: P/E 54.6, Favorable on our tests, recalculated for the week of 2026-07-272026-07-31: P/E 54.6, Favorable on our tests, recalculated for the week of 2026-07-312026-07-31: P/E 43.4, Favorable on our tests, recorded live 2026-08-032026-08-07: P/E 43.4, Favorable on our tests, recalculated for the week of 2026-08-072026-08-07: P/E 46.0, Favorable on our tests, recorded live 2026-08-102026-08-14: P/E 46.0, Favorable on our tests, recalculated for the week of 2026-08-142026-08-14: P/E 47.3, Favorable on our tests, recorded live 2026-08-172026-08-21: P/E 47.3, Favorable on our tests, recalculated for the week of 2026-08-212026-08-21: P/E 48.3, Favorable on our tests, recorded live 2026-08-242026-08-27: P/E 48.3, Favorable on our tests, recalculated for the week of 2026-08-272026-08-28: P/E 48.3, Favorable on our tests, recalculated for the week of 2026-08-282026-08-28: P/E 48.3, Favorable on our tests, recalculated for the week of 2026-08-302026-08-28: P/E 47.7, Favorable on our tests, recorded live 2026-08-312026-09-04: P/E 47.7, Favorable on our tests, recalculated for the week of 2026-09-052026-09-04: P/E 52.5, Favorable on our tests, recorded live 2026-09-072026-09-11: P/E 52.5, Favorable on our tests, recalculated for the week of 2026-09-122026-09-11: P/E 48.8, Favorable on our tests, recorded live 2026-09-142026-09-18: P/E 48.8, Favorable on our tests, recalculated for the week of 2026-09-192026-09-18: P/E 46.4, Favorable on our tests, recorded live 2026-09-212026-09-25: P/E 48.8, Favorable on our tests, recalculated for the week of 2026-09-262026-09-25: P/E 48.8, Mixed on our tests, recorded live 2026-09-282026-10-02: P/E 41.3, Mixed on our tests, recalculated for the week of 2026-10-032026-10-02: P/E 41.3, Mixed on our tests, recorded live 2026-10-052026-10-09: P/E 43.1, Mixed on our tests, recalculated for the week of 2026-10-102026-10-09: P/E 43.1, Mixed on our tests, recorded live 2026-10-122026-10-16: P/E 42.0, Mixed on our tests, recalculated for the week of 2026-10-172026-10-16: P/E 42.0, Mixed on our tests, recorded live 2026-10-192026-10-23: P/E 40.4, Mixed on our tests, recalculated for the week of 2026-10-242026-10-23: P/E 40.4, Mixed on our tests, recorded live 2026-10-262026-10-30: P/E 9.7, Mixed on our tests, recalculated for the week of 2026-10-312026-10-30: P/E 9.7, Mixed on our tests, recorded live 2026-11-0220.040.0Jul 24Aug 17Sep 11Oct 6Oct 30
Favorable on our testsMixed on our tests

Not every point was recorded live. Points marked recalculated are worked out from the metrics tickerseer archived that week.

Selected weeks: the first, the latest, every week the rating moved, and the cheapest and dearest.

WeekCurrent P/EPremium to normal P/ERating
2026-07-25P/E 54.6-68%Favorable on our tests (recalculated)
2026-09-28P/E 48.8-71%Mixed on our tests (across a rating rules change)
2026-10-31P/E 9.7not meaningfulMixed on our tests (recalculated)
2026-11-02P/E 9.7not meaningfulMixed on our tests ← now
Show all 32 readings
WeekCurrent P/EPremium to normal P/ERating
2026-07-25P/E 54.6-68%Favorable on our tests (recalculated)
2026-07-27P/E 54.6-68%Favorable on our tests (recalculated)
2026-07-31P/E 54.6-68%Favorable on our tests (recalculated)
2026-08-03P/E 43.4-75%Favorable on our tests
2026-08-07P/E 43.4-75%Favorable on our tests (recalculated)
2026-08-10P/E 46.0-73%Favorable on our tests
2026-08-14P/E 46.0-73%Favorable on our tests (recalculated)
2026-08-17P/E 47.3-72%Favorable on our tests
2026-08-21P/E 47.3-72%Favorable on our tests (recalculated)
2026-08-24P/E 48.3-72%Favorable on our tests
2026-08-27P/E 48.3-72%Favorable on our tests (recalculated)
2026-08-28P/E 48.3-72%Favorable on our tests (recalculated)
2026-08-30P/E 48.3-72%Favorable on our tests (recalculated)
2026-08-31P/E 47.7-72%Favorable on our tests
2026-09-05P/E 47.7-72%Favorable on our tests (recalculated)
2026-09-07P/E 52.5-69%Favorable on our tests
2026-09-12P/E 52.5-69%Favorable on our tests (recalculated)
2026-09-14P/E 48.8-71%Favorable on our tests
2026-09-19P/E 48.8-71%Favorable on our tests (recalculated)
2026-09-21P/E 46.4-73%Favorable on our tests
2026-09-26P/E 48.8-71%Favorable on our tests (recalculated)
2026-09-28P/E 48.8-71%Mixed on our tests (across a rating rules change)
2026-10-03P/E 41.3-76%Mixed on our tests (recalculated)
2026-10-05P/E 41.3-76%Mixed on our tests
2026-10-10P/E 43.1-75%Mixed on our tests (recalculated)
2026-10-12P/E 43.1-75%Mixed on our tests
2026-10-17P/E 42.0-75%Mixed on our tests (recalculated)
2026-10-19P/E 42.0-75%Mixed on our tests
2026-10-24P/E 40.4-76%Mixed on our tests (recalculated)
2026-10-26P/E 40.4-76%Mixed on our tests
2026-10-31P/E 9.7not meaningfulMixed on our tests (recalculated)
2026-11-02P/E 9.7not meaningfulMixed on our tests ← now

Frequently asked questions

Is Alnylam Pharmaceuticals stock overvalued?

Alnylam Pharmaceuticals trades at a current P/E of 9.0. Its published historical normal P/E is 170.7, more than six times that, so there is no meaningful premium or discount to quote. tickerseer currently rates it mixed on our tests.

What is Alnylam Pharmaceuticals's fair value and PEG?

Alnylam Pharmaceuticals trades at a current P/E of 9.0, a forward growth estimate of -20.2%.

Has tickerseer's rating of Alnylam Pharmaceuticals changed?

tickerseer's rating moved from favorable on our tests (2026-07-25) to mixed on our tests (2026-11-02). New rating rules took effect in the week of 2026-09-28, and this rating moved across that change, so part of the move may come from the new rules rather than the company.

What is the analyst price target for Alnylam Pharmaceuticals?

The mean Wall Street price target for Alnylam Pharmaceuticals is $310.89 across 27 analysts, 99.4% above the current price. tickerseer's SeerForecast verdict is formed independently of analyst targets.

Industry: Biotech. Create a free account to see the full analysis: the SeerAI score, its five quality sub-scores, valuation history, and an AI research note where we have one. Options setups and metric history are part of the paid plans.

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